Easy MCQ +4 / -1 PYQ · JEE Mains 2021

With respect to drug-enzyme interaction, identify the wrong statement.

  1. A Allosteric inhibitor changes the enzyme's active site
  2. B Allosteric inhibitor competes with the enzyme's active site Correct answer
  3. C Competitive inhibitor binds to the enzyme's active site
  4. D Non-Competitive inhibitor binds to the allosteric site

Solution

<p>Allosteric inhibitor combines at allosteric site and not the active site.</p> <p>Drugs inhibit the attachment of substrate on active site of enzymes in two different ways :</p> <p>(i) Drugs compete with the natural substrate for their attachment on the active sites of enzymes. Such drugs are called competitive inhibitors.</p> <p>(ii) Some drugs do not bind to the enzyme's active site. These bind to a different site of enzyme which is called allosteric site. This binding of inhibitor at allosteric site changes the shape of the active site in such a way that substrate cannot recognise it.This is also called non-competitive inhibitor.</p> <p>Non-competitive inhibitor changes the active site of enzyme after binding at allosteric site.</p>

About this question

Subject: Chemistry · Chapter: Chemistry in Everyday Life · Topic: Drugs and Medicines

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